Members-only rates
4.5 / 5 Excellent

21C Museum Hotel St Louis

21C Museum Hotel St Louis
21C Museum Hotel St Louis – St. Louis, MO
21C Museum Hotel St Louis – St. Louis, MO
Check in 4:00 PM
Check out 11:00 AM

About 21C Museum Hotel St Louis

Comfortable Accommodations Rooms feature air-conditioning, private bathrooms, and modern amenities such as free WiFi, flat-screen TVs, and work desks. Additional comforts include bathrobes, hairdryers, and free toiletries. Exceptional Facilities Guests can enjoy a spa and wellness center, indoor swimming pool, terrace, and fitness room. The hotel offers yoga and fitness classes, a steam room, hot tub, and sauna. Dining Experience The modern restaurant serves Spanish cuisine for dinner, complemented by a bar. American breakfast is available each morning. Prime Location Located in St. Louis city center, the hotel is 1.2 mi from the Gateway Arch and near attractions like Laclede's Landing and Forest Park. St. Louis Lambert International Airport is 13 mi away.

Amenities

  • On-site parking
  • 24-hour front desk
  • Meeting space
  • Fitness center
  • On-site dining
  • Valet parking
  • Bar / lounge
  • Café / coffee shop
  • Breakfast available
  • Business center
  • Concierge
  • Dry cleaning
  • Self-service laundry
  • Luggage storage
  • Full kitchen / kitchenette
  • In-room refrigerator
  • Pool
  • Spa / sauna
  • Pet friendly
  • Wheelchair accessible
  • Smoke-free property
  • Air conditioning
  • Elevator
  • In-room safe

Reviews

4.5 / 5
Excellent 2063 reviews
  • Engine customer Aug 2026

    Tiffany, at the front desk, was super friendly, very helpful, and just the service a tourist needs!!!

  • Engine customer Aug 2026

    The hotel itself was great. Amenities were good. Staff was great if I had one item that I think more people visiting an upscale hotel would like is a better variety of food available. I noticed a lot of people going out for food or getting food elsewhere, as I said the hotel itself it’s wonderful. The art was magnificent. The surroundings themselves within the hotel were beautiful. I would gladly recommend this hotel to anyone looking for a unique upscale type of hotel in St. Louis.

  • Engine customer Aug 2026

    Everything was pretty good with room, but air unit went out in 313, however the quickly moved us next door and gave us a 50 room credit for food. One thing was disappointing was the restaurant, the steak had to be replaced and even when they did it at medium rare it just wasnt that great. Reminded me of our grilled steak at home, just nothing special for that price. The half chicken was dry and so small for 38 bucks.

  • Engine customer Aug 2026

    Beautiful hotel. I loved my stay. The staff was great! I can’t wait to stay at another 21C property. The museum was fantastic. You can have an adventure without leaving the hotel :)

  • Engine customer Aug 2026

    The artistry of the bldg and art display were a plus.

  • Engine customer Aug 2026

    Great place to stay!

  • Engine customer Aug 2026

    Rooms are spacious, clean, and stylish.

  • Engine customer Aug 2026

    Amazing fitness facilities! Staff was incredible. Great food too. Only complaint was the pillows were not very comfortable and the rooms feel cramped. But very minor issues.

  • Engine customer Aug 2026

    The property was clean, comfortable, and well maintained. The staff was friendly and helpful throughout my stay. I enjoyed the location and overall atmosphere. It was a pleasant experience, and I would consider staying here again.

  • Engine customer Aug 2026

    The hot tub and pool were great. The room was okay. The service at the restaurant and bar was great as well.

  • Engine customer Aug 2026

    The room and the hallways were not clean. Some hotel staff were not friendly. Didn’t feel comfortable.

  • Engine customer Aug 2026

    I loved the stay at this hotel. Once inside, everything and everyone was beautiful. The only thing that could have been better was the parking situation. Even so, I found a place to self-park each night and felt safe going and coming.

  • Engine customer Aug 2026

    Horrible valet customer service

  • Engine customer Aug 2026

    Location

  • Engine customer Aug 2026

    Location, nicely decorated, the art was wonderful, and the bar area was great. Pillows and bed was hard, hotel staff was not the most friendly, valet parking is ridiculously priced. I thought the rooms were overpriced as well.

  • Engine customer Aug 2026

    It’s a great property but I left my pillow and I was led to believe ott could be mailed to me but it hasn’t so I don’t think anyone cared… Leaving my pillow and being told it would be sent and it wasn’t…

  • Engine customer Aug 2026

    The stay was fine. A little bit of an older building, not really my style but nothing wrong with it. I did pay the $50 a day for valet so my car wouldn’t get stolen so be mindful of that.

  • Engine customer Aug 2026

    Such an amazing place. We were on a road trip and needed a place where everything was there. This was it! We LOVED the pool and spa. And the art exhibit was beautiful!

  • Engine customer Aug 2026

    This hotel was a fun experience for our family with really nice spacious and clean rooms and an amazing pool and fitness center with lap lanes. There is a coffee shops with breakfast for purchase but be prepared for really long wait times for food. Great location for downtown experiences like Busch Stadium Union Station and City Museum

  • Engine customer Aug 2026

    The parking

Frequently asked questions about 21C Museum Hotel St Louis

Does 21C Museum Hotel St Louis have free Wi-Fi?
Yes, 21C Museum Hotel St Louis offers free Wi-Fi for all guests.
Does 21C Museum Hotel St Louis offer parking?
Yes, 21C Museum Hotel St Louis offers both self-parking and valet parking. Fees may apply.
Does 21C Museum Hotel St Louis have meeting spaces, conference centers, or conference rooms?
Yes. 21C Museum Hotel St Louis offers meeting spaces for business and group use. Banquet and reception facilities are also available.
Does 21C Museum Hotel St Louis have a fitness center?
Yes, 21C Museum Hotel St Louis features an on-site fitness center for guests. Additional wellness amenities include spa, sauna, pool.
Where is 21C Museum Hotel St Louis located, and how walkable is the area?
21C Museum Hotel St Louis is located at 1528 Locust street, St. Louis, MO 63103. With a Walk Score of 89, the area is rated Very Walkable. Most errands can be completed on foot, with public transit and rideshare easily accessible.

What's nearby

Map of points of interest near 21C Museum Hotel St Louis
  • athletics at the 1904 Summer Olympics 0.4 mi
  • America's Center Convention Complex 0.6 mi
  • Pruitt–Igoe 0.8 mi
  • Louisiana Territory 1.0 mi
  • Gateway Arch 1.1 mi
  • Missouri Botanical Garden 3.3 mi
  • Washington University in St. Louis 5.6 mi

Why no public rates?

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